CeBiTec Colloquium (unscheduled)
date | Tuesday, July 10th 2012, 16 c.t. | |
location | G2-104, CeBiTec Building | |
speaker | Prof. Dr. Otto HolstDivision of Structural Biochemistry, | |
title | Structure and function of certain bacterial glycolipids | |
abstract | Glycolipids are amphiphilic membrane components that occur in all kingdoms of organisms, namely plants, animals including man, and bacteria. They represent a group of molecules possessing one or more monosaccharide units linked by a glycosyl linkage to a hydrophobic moiety like ceramide, acylglycerol, prenyl phosphate, or acylated sugars. Such glycoconjugates represent important factors of membrane and cell surface stabilization, and also play significant roles in various biological processes, like cell-cell communication or receptor modulation. The presentation deals with some examples of bacterial glycolipids, like the glucosyldiacylglycerols from Enterococcus faecalis and their impact on biofilm production and adhesion, the rough-type lipopolysaccharide (LPS) from Acinetobacter lwoffii and its role in allergy protection, and the rough-type LPS from Yersinia pestis and why it is so important in plague. | |
host | Prof. Dr. Karsten Niehaus |