My address:
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| Name: | Dr. Heiko Neuweger |
| Postal Address: | Universität Bielefeld |
| Bioinformatics Resource Facility |
| 33594 Bielefeld |
| E-mail: | Heiko.Neuweger CeBiTec.Uni-Bielefeld.DE |
| Office: | V6-139 |
| Office Phone: | +49-(0)521-106-4823 |
| Office Fax: | +49-(0)521-106-6419 |
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Research Interests
- Computational Metabolomics
- Algorithms in Mass Spectrometry
- Metabolic Flux Analysis
- Metagenomics
- Multi-Omics Data Visualization & Data Integration
Publications
Peer-reviewed journal publications
| [12] |
J. Schneider, F.-J. Vorhölter, E. Trost, J. Blom, Y. R. Musa, H. Neuweger, K. Niehaus, S. Schatschneider, A. Tauch and A. Goesmann (2010)
CARMEN: In silico reconstruction of organism-specific metabolic networks using SBML.
Genetics and Molecular Research: 9, (3); DOI 10.4238/vol9-3gmr901
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| [11] |
N. Gehlenborg, S. I. O'Donoghue, N. S. Baliga, A. Goesmann, M. A. Hibbs, H. Kitano, O. Kohlbacher, H. Neuweger, R. Schneider, D. Tenenbaum, A. C. Gavin (2010)
Visualization of omics data for systems biology.
Nat Methods 7(3 Suppl): S56-68; PubMed ID: 20195258
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| [10] |
H. Neuweger, M. Persicke, S. Albaum, T. Bekel, M. Dondrup, A. Huser, J. Winnebald, J. Schneider, J. Kalinowski, A. Goesmann
Visualizing Post Genomics Data-sets on customized Pathway Maps by ProMeTra - aeration-dependent gene expression and metabolism of Corynebacterium glutamicum as an example.
BMC Systems Biology, Vol. 3, No. 1. (2009), 82.
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| [9] |
M. Dondrup, S. P. Albaum, T. Griebel, K. Henckel, S. Jünemann, T. Kahlke, C. K. Kleindt, H. Küster, B. Linke, D. Mertens, V. Mittard-Runte, H. Neuweger, K. J. Runte, A. Tauch, F. Tille, A. Pühler and A. Goesmann
EMMA 2 - A MAGE-compliant system for the collaborative analysis and integration of microarray data.
BMC Bioinformatics 2009, 10:50
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| [8] |
T. Bekel, K. Henckel, H. Küster, F. Meyer, V. Mittard Runte, H. Neuweger, D. Paarmann, O. Rupp, M. Zakrzewski, A. Pühler, J. Stoye, A. Goesmann (2009)
The Sequence Analysis and Management System ? SAMS-2.0: Data management and sequence analysis adapted to changing requirements from traditional Sanger sequencing to ultrafast sequencing technologies.
J Biotechnol 140(1-2): 3-12
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| [7] |
H. Neuweger, S. P. Albaum, M. Dondrup, M. Persicke, T. Watt, K. Niehaus, J. Stoye, A. Goesmann (2008)
MeltDB: A software platform for the analysis and integration of metabolomics experiment data.
Bioinformatics; doi: 10.1093/bioinformatics/btn452
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| [6] |
L. Krause, N. Diaz, R. Edwards, K. H. Gartemann, H. Krömeke, H. Neuweger, A. Pühler, K. J. Runte, A. Schlüter, J. Stoye, R. Szczepanowski, A. Tauch, A. Goesmann (2008)
Taxonomic composition and gene content of a methane-producing microbial community isolated from a biogas reactor.
J Biotechnol 136(1-2): 91-101; PubMed ID: 18611419
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| [5] |
A. Schlüter, T. Bekel, N. Diaz, M. Dondrup, R. Eichenlaub, K. H. Gartemann, I. Krahn, L. Krause, H. Krömeke, O. Kruse, J. H. Mussgnug, H. Neuweger, K. Niehaus, A. Pühler, K. J. Runte, R. Szczepanowski, A. Tauch, A. Tilker, P. Viehoever, A. Goesmann (2008)
The metagenome of a biogas-producing microbial community of a production-scale biogas plant fermenter analysed by the 454-pyrosequencing technology.
J Biotechnol 136(1-2): 77-90; PubMed ID: 18597880
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| [4] |
H. Neuweger, J. Baumbach, S. Albaum, T. Bekel, M. Dondrup, A. T. Hüser, J. Kalinowski, S. Oehm, A. Pühler, S. Rahmann, J. Weile, A. Goesmann (2007)
CoryneCenter - An online resource for the integrated analysis of corynebacterial genome and transcriptome data.
BMC Syst Biol 1(1): 55; PubMed ID: 18034885
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| [3] |
B. Linke, A. C. McHardy, H. Neuweger, L. Krause, F. Meyer (2006)
The REGANOR gene prediction server for prokaryotic genomes and a database of high quality gene predictions for prokaryotes.
Applied Bioinformatics 5(3): 193-8
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| [2] |
R. Overbeek, T. Begley, R. M. Butler, J. V. Choudhuri, N. Diaz, H. Y. Chuang, M. Cohoon, V. de Crécy-Lagard, T. Disz, R. Edwards, M. Fonstein, E. D. Frank, S. Gerdes, E. M. Glass, A. Goesmann, L. Krause, B. Linke, A. C. McHardy, F. Meyer, A. Hanson, D. Iwata-Reuyl, R. Jensen, N. Jamshidi, M. Kubal, N. Larsen, H. Neuweger, C. Rückert, G. Olsen, R. Olson, A. Osterman, V. Portnoy, G. D. Pusch, D. A. Rodionov, J. Steiner, R. Stevens, I. Thiele, O. Vassieva, Y. Ye, O. Zagnitko, V. Vonstein (2005)
The Subsystems Approach to Genome Annotation and its Use in the Project to Annotate 1000 Genomes
Nucleic Acids Res 33(17):
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| [1] |
A. Goesmann, B. Linke, D. Bartels, M. Dondrup, L. Krause, H. Neuweger, S. Oehm, T. Paczian, A. Wilke, F. Meyer (2005)
BRIGEP - The BRIDGE-based Genome-Transcriptome-Proteome Browser.
Nucleic Acids Res 33: W710-W160
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Current and Recent Research Projects
MeltDB: A Framework for the Analysis and Integration of Metabolomics Experiment Data
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The MeltDB open source framework is designed to provide analysis methods for raw GC- and LC-MS datasets and offers methods to combine the respective results. A flexible tool pipeline implemented in MeltDB allows both the import of preprocessed data as well as the integration of existing open source analysis packages such as XCMS, MassSpecWavelet or metaB. For the identification of metabolites based on mass spectra the freely available GMD database is queried. Additionally, user defined libraries in the NIST format can be imported. Read more... |
ProMeTra: Multi-Omics Viewer
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The web based ProMeTra system is designed to provide visualization methods for multi-omics datasets. The open vector based graphics format SVG is used to display or animate the datasets on metabolic pathway maps. Read more... |
CoryneCenter: An online resource for the integrated analysis of corynebacterial genome and transcriptome data
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CoryneCenter is an online resource for the integrated analysis of corynebacterial genome and transcriptome data. |
Theses (Bachelor, Master, Diploma)
Jörn Winnebald (Bachelor): Visualization of Transcriptomic and Metabolomics Datasets
Nils Hoffmann (Diploma): Development and Analysis of Methods for Comparison of Multiple Chromatograms from Liquid and Gas Chromatography - Mass Spectrometry
Daniel Dörr (Bachelor): A Feature Based Multiple Alignment Approach for Gas Chromatography - Mass Spectrometry Experiments
Jörn Winnebald (Master): Organism wide reconstruction of stoichiomteric matrices supported by genome annotation and metabolomics experiment data
Nikolas Kessler (Master): An online multi-user collaboration tool for metabolomics data
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