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Dr. Hanna Marie Schilbert


    Current research focus

    • comparative genomics
    • structural variants
    • variant impact prediction / variant annotation
    • phylogenetic analyses
    • identification of economically and nutritional relevant loci
    • nutrigenetics/genomics
    • flavonoid biosynthesis
    • reduction of antinutrients
    • analysis of seed quality parameters
    • RNA-Seq analysis
    • ...

    Teaching

    • Python Programming in Genome Research (for Beginners)

      ekVV


    Projects for students: Please send me an email if you are interested in a project involving genomics/transcriptomics/bioinformatics/flavonoid biosynthesis/reduction of antinutrients/analysis of seed quality in Brassica napus.


    Publications

    • Schilbert, H. M.*, Busche M.*, Sáez V., Angeli A., Weisshaar B., Martens S., Stracke R. (2024). Generation and characterisation of an Arabidopsis thaliana f3h/fls1/ans triple mutant that accumulates eriodictyol derivatives. BMC Plant Biology 2024. doi:10.1186/s12870-024-04787-1
      link to publication(peer-reviewed) PDF bioRxiv preprint PUB *shared first authorship
    • Schilbert, H. M.*, Holzenkamp K.*, Viehöver P., Holtgräwe D., Möllers C. (2023). Homoeologous non-reciprocal translocation explains a major QTL for seed lignin content in oilseed rape (Brassica napus L.). Theoretical and Applied Genetics 2023. doi:10.1007/s00122-023-04407-w
      link to publication(peer-reviewed) PDF bioRxiv preprint PUB github *shared first authorship
    • Schilbert H. M., Busche M., Viehöver P., Weisshaar B., Stracke R. (2023). De novo ONT long read assembly of the A. thaliana f3h/fls1/ans triple mutant. Bielefeld University.
      link to data publication PUB
    • Schilbert, H. M.*, Pucker B.*, Ries D., Viehöver P., Micic Z., Dreyer F., Beckmann K., Wittkop B., Weisshaar B., Holtgräwe D. (2022). Mapping-by-Sequencing Reveals Genomic Regions Associated with Seed Quality Parameters in Brassica napus. Genes 2022. doi:10.3390/genes13071131
      link to publication(peer-reviewed) PDF bioRxiv preprint PUB github *shared first authorship
    • Pellegrinelli V., Rodriguez-Cuenca S., Rouault C., Figueroa-Juarez E., Schilbert H., Virtue S., Moreno-Navarrete J. M., Bidault G., Vazquez Borrego M. C., Dias A. R., Pucker B., Dale M., Campbell M., Carobbio S., Lin Y. H., Vacca M., Aron-Wisnewsky J., Mora S., Masiero M. M., Emmanouilidou A., Mukhopadhyay S., Dougan G., den Hoed M., Loos R. J. F., Fernandez-Real J. M., Chiarugi D., Clement K. and Vidal-Puig A. (2022). Dysregulation of macrophage PEPD in obesity determines adipose tissue fibro-inflammation and insulin resistance. Nature metabolism 2022. doi:10.1038/s42255-022-00561-5.
      link to publication(peer-reviewed) PDF Research Square preprint PUB
    • Schilbert, H. M., Glover, B. J. (2022). Analysis of flavonol regulator evolution in the Brassicaceae reveals MYB12, MYB111 and MYB21 duplications and MYB11 and MYB24 gene loss. BMC Genomics 2022. doi:10.1186/s12864-022-08819-8
      link to publication(peer-reviewed) PDF bioRxiv preprint PUB
    • Schilbert, H. M., Schöne M., Baier T., Busche M., Viehöver P., Weisshaar B., Holtgräwe D. (2021). Characterization of the Brassica napus flavonol synthase gene family reveals bifunctional flavonol synthases. Frontiers in Plant Science 2021. doi:10.1101/2021.06.30.450533
      link to publication(peer-reviewed) PDF bioRxiv preprint PUB github
    • Lauxmann M. A., Vazquez D. S., Schilbert, H. M., Neubauer P. R., Lammers K. M., Dodero V. I. (2021). From celiac disease to coccidia infection and vice-versa: The polyQ peptide CXCR3-interaction axis. BioEssays 2021. doi:10.1002/bies.202100101
      link to publication(peer-reviewed) PDF PUB
    • Vazquez D. S.*, Schilbert H. M.*, Dodero V. I. (2021). Molecular and Structural Parallels between Gluten Pathogenic Peptides and Bacterial-Derived Proteins by Bioinformatics Analysis. International Journal of Molecular Sciences 2021, 22(17), 9278. doi:10.3390/ijms22179278
      link to publication(peer-reviewed) PDF PUB *shared first authorship
    • Schilbert H. M., Kleinbölting N, Weisshaar B, Pucker B. (2021). Arabidopsis thaliana methylation pattern analysis based on ONT sequence reads. Bielefeld University.
      link to data publication PUB
    • Pucker B., Reiher F. and Schilbert, H. M. (2020). Automatic identification of players in the flavonoid biosynthesis with application on the biomedicinal plant Croton tiglium. Plants 2020, 9, 1103. doi:10.3390/plants9091103.
      link to publication(peer-reviewed) PDF bioRxiv preprint PUB github
    • Schilbert H. M., Rempel A. and Pucker B. (2020). Comparison of read mapping and variant calling tools for the analysis of plant NGS data. Plants 2020. doi:10.3390/plants9040439.
      link to publication(peer-reviewed) PDF bioRxiv preprint PUB data
    • Pucker B. & Schilbert H. (2019). Genomics and Transcriptomics Advance in Plant Sciences. Molecular Approaches in Plant Biology and Environmental Challenges. Springer 2019. ISBN 978-981-15-0690-1. doi:10.1007/978-981-15-0690-1
      link to publication(peer-reviewed book chapter) PUB
    • Pucker B.,Schilbert, H. M. , Schumacher S. F. (2019). Integrating Molecular Biology and Bioinformatics Education. Journal of Integrative Bioinformatics 2019. doi:10.1515/jib-2019-0005.
      link to publication(peer-reviewed) PDF preprint PUB
      Applied Genome Research (github) Molecular Methods in Genome Research (github)
    • Schilbert H. M., Pellegrinelli V., Rodriguez-Cuenca S., Vidal-Puig A. & Pucker B. (2018). Harnessing natural diversity to identify key amino acid residues in prolidase. bioRxiv 2018 423475. doi:10.1101/423475
      link to publication PUB