| date | | Monday, June 7th 2010, 17 c.t. |
| location | | G2-104, CeBiTec Building |
| speaker | | Prof. Dr. Jean Pierre JacquotFaculté des Sciences, Université Henri Poincaré, Vandoeuvre, France
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| title | | Thioredoxin and glutaredoxin play a prominent role in stress defence and iron sulfur assembly in plants |
| | | Thioredoxins have long been recognized as key regulators of the photosynthetic activity in chloroplasts. Genomic advances have indicated that there is very large number of isoforms of thioredoxins and of related proteins, glutaredoxins, in plants compared to non photosynthetic eukaryotes. This is accompanied by differential subcellular localization and different modes of reduction for these proteins. Recent evidence involving thioredoxins and glutaredoxins in stress response will be presented concerning the regeneration of peroxiredoxins, glutathione peroxidases and methionine sulfoxide reductases. In addition, the role of some glutaredoxins in iron sulfur assembly will be discussed. As proteins with iron sulfur centers are essential for many reactions including the functioning of the mitochondrial and chloroplastic electron transfer chains, glutaredoxin defects are accompanied by a deregulation of iron homeostasis and an oxidative stress response, inducing several genetic diseases in human and dysfunctionings in plants.
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| host | | Prof. Dr. Karl-Josef Dietz
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