Large Scale Genomics and Big Data Bioinformatics
This research area focuses on genome research on bacteria relevant for biotechnology, agriculture and the environment, on structural and functional decoding of genomes of crop plants, animal cell cultures and microalgae, on metagenomics analysis of microbial communities as well as on elucidation of the function and interaction of genes and genomes with post-genomics and bioinformatics methods.
Speakers: Prof. Dr. J. Kalinowski and Prof. Dr. Jens Stoye

Selection of current projects
- BIOGAS-GeneMining – Charakterisierung des genetischen und enzymatischen Potentials von Biogas-Mikrobiomen mittels Metaanalyse von Metagenomdatensätzen
Responsible: Prof. Dr. A. Pühler
Funded by: Federal Ministry of Food and Agriculture (BMEL) - de.NBI – German Network for Bioinformatics infrastructure
Responsible: Prof. Dr. A. Pühler
Funded by: Federal Ministry of Education and Research (BMBF)
Twitter: @denbiOffice - SIMBA – Sustainable innovation of microbiome applications in food systems
Responsible: Prof. Dr. A. Sczyrba
Funded by: European Commission (EU H2020)
Twitter: @SIMBAproject_EU - EOSC-Life: Providing an open collaborative space for digital biology in Europe
Responsible: Prof. Dr. A. Sczyrba
Funded by: European Commission (EU H2020) - HiPoAF – Unleashing the hidden potential of the anaerobic fungi
Responsible: Prof. Dr. A. Sczyrba
Funded by: German Research Foundation (DFG, DACH) - ELIXIR Compute Platform: Hybrid Cloud
Responsible: Prof. Dr. A. Sczyrba
Funded by: ELIXIR
Twitter: @ELIXIREurope - Plasmidome – Machine Learning methods for data-driven discovery of antibiotic resistance plasmid dissemination and evolution
Responsible: Prof. Dr. A. Sczyrba
Funded by: Novo Nordisk Foundation - de.NBI Cloud: Cloud Solutions of the German Network for Bioinformatics Infrastructure (de.NBI) at Bielefeld University
Responsible: Prof. Dr. A. Sczyrba, Prof. Dr. Jens Stoye
Funded by: Federal Ministry of Education and Research (BMBF) - PANGAIA – Pan-genome Graph Algorithms and Data Integration
Responsible: Prof. Dr. A. Schönhuth (coordinator), Prof. Dr. J. Stoye
Funded by: European Commission (EU H2020, RISE)
Twitter: @PangaiaProject - ALPACA - ALgorithms for PAngenome Computational Analysis
Responsible: Prof. Dr. A. Schönhuth (coordinator), Prof. Dr. J. Stoye
Funded by: European Commission (EU H2020, MSCA-ITN) - de.NBI – German Network of Bioinformatics Infrastructure – BiGi – Bioinformatics Ressource Center for Microbial Genome Research in Biotechnology and Medicine
Responsible: Prof. Dr. J. Stoye
Funded by: Federal Ministry of Education and Research (BMBF)
Twitter: @denbiOffice - CLIB-Kompetenzzentrum Biotechnologie (CKB)
Coordination: Prof. Dr. V.F. Wendisch
Subprojects: Prof. Dr. J. Kalinowski, Prof. Dr. B. Weisshaar
Founded by: Europäischer Fonds für regionale Entwicklung (EFRE-NRW) - RaPEQ – Pflanzenzüchtungsforschung-Verbundvorhaben: Rapssaat als einheimische Quelle von hochwertigem Protein für die menschliche Ernährung
Responsible: Prof. Dr. B. Weisshaar
Funded by: Federal Ministry of Education and Research (BMBF) - DIGIRAS - Optimierung der landgestützten Fischproduktion in digitalen Kreislauf-Aquakultursystemen der nächsten Generation
Responsible: Prof. Dr. J. Kalinowski
Funded by: ERA-NET Cofund (BMBF) - Maßgeschneiderte Inhaltsstoffe 2 - Verbundvorhaben: 'Entwicklung eines Systems für das Design und die Synthese von maßgeschneiderten Peptiden für die Behandlung von Polymeren im Vorfeld der Kunststoff-Metallisierung (PepMetal) - Teilprojekt C'
Responsible: Prof. Dr. J. Kalinowski
Funded by: Federal Ministry of Education and Research (BMBF) - Rhinobiome: Detection of shifts in microbiome composition in chronic rhinosinusitis by an optimized analytical workflow
Responsible: Prof. Dr. J. Kalinowski, Prof. Dr. A. Sczyrba
Funded by: Anschubfonds Medizinische Forschung der Universität Bielefeld - Taxon-OMICS: Neue Herangehensweisen zur Entdeckung und Benennung von Arten und Biodiversität / Teilprojekt: „Phylogenomik der Gattung Hypoxylon basierend auf 50 neuen, hochwertigen Genomen und mit besonderem Schwerpunkt auf dem H. rubiginosum-Komplex“
Responsible: Prof. Dr. J. Kalinowski
Funded by: Deutsche Forschungsgemeinschaft (DFG) - BioProMare: EXPLOMARE - Erforschung und Exploitation des Biosynthesepotentials mariner Aktinobakterien
Responsible: Prof. Dr. J. Kalinowski
Funded by: Federal Ministry of Education and Research (BMBF) - HotAcidFACTORY (Sulfolobus acidocaldarius als neuartige thermoacidophile Biofabrik)
Responsible: Prof. Dr. J. Kalinowski
Funded by: Federal Ministry of Education and Research (BMBF) - PW-Exposed – Produced water fractionation and advanced chemical and toxicological characterization using sensitive life stages of marine fish species
Responsible: Prof. Dr. J. Kalinowski
Funded by: Norwegian Research Fund