Bielefeld University

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Bioinformatics

Research in Bioinformatics spans genome and pangenome analysis, metagenomics, multi-omics, bioimage analysis, algorithmic cheminformatics and systems chemistry. The area develops computational, mathematical, and data-driven methods, ranging from scalable data analysis and artificial intelligence, including machine learning, to formal models of molecular transformations, metabolic networks, and microbial communities. These approaches help to understand and design biological and biochemical systems and support applications in biotechnology, medicine, agriculture, environmental research and sustainable bioproduction.

Speakers: Prof. Dr. A. Sczyrba and Prof. Dr. D. Merkle

Selection of current projects

  • 2022-ECP2 ELIXIR Hybrid Cloud und 2022-Travel Funds for cross-Node activities
    Responsible: Prof. Dr. A. Sczyrba
    Funded by: ELIXIR
  • BioProtect - Advancing area-based management tools to accelerate the protection and restoration of marine biodiversity across the European sea basins
    Responsible: Prof. Dr. T. Nattkemper
    Funded by: European Commission
  • Comparative analysis of deleterious genetic variation in wild animal populations
    Responsible: Prof. Dr. J. Hoffman
    Funded by: Deutsche Forschungsgemeinschaft (DFG)
  • EOSC-ENTRUST: A European Network of TRUSTed research environments
    Responsible: Prof. Dr. A. Sczyrba
    Funded by: European Commission (EU)
  • EOSC-Life (Charite): Providing an open collaborative space for digital biology in Europe
    Responsible: Prof. Dr. A. Sczyrba
    Funded by: European Commission (EU)
  • Erhöhung der Protein-Nutzungseffizienz bei Backweizen durch innovative Züchtungsforschung an der MAGIC-WHEAT-Population WM-800 für effektiven Klimaschutz in der Getreidewertschöpfungskette (MAGIC-KlimaBack)
    Responsible: Prof. Dr. R. Schmidt-Schippers
    Funded by: Federal Ministry of Food and Agriculture (BMEL)
  • MicrobiomProCheck
    Responsible: Prof. Dr. R. Heyer (coordinator), Prof. Dr. A. Sczyrba
    Funded by: European Regional Development Fund (EFRE)
  • MicroGenUniBi: de.NBI-Ressourcenzentrum für mikrobielle Genomforschung in Biotechnologie und Medizin an der Uni Bielefeld
    Responsible: Prof. Dr. J. Stoye & Prof. Dr. R. Heyer
    Funded by: Federal Ministry of Education and Research (BMBF)
  • Modulation hypoxischer Antworten durch RADICAL-INDUCED CELL DEATH 1 in Arabidopsis thaliana
    Responsible: Prof. Dr. R. Schmidt-Schippers
    Funded by: Deutsche Forschungsgemeinschaft (DFG)
  • NUM 2.0 - GenSurv: Netzwerk Universitätsmedizin 2.0 - Genomic Pathogen Surveillance and Translational Research
    Responsible: Prof. Dr. A. Sczyrba
    Funded by: Federal Ministry of Education and Research (BMBF)
  • NFDI DataPLANT – Daten in Pflanzen-Grundlagenforschung
    Responsible:
    Prof. Dr. A. Bräutigam
    Funded by: Deutsche Forschungsgemeinschaft (DFG)
  • NFDI4BioDiversity - A Consortium for the National Research Data Infrastructure
    Responsible: Prof. Dr. J. StoyeFunded by: Deutsche Forschungsgemeinschaft (DFG)
  • PANGAIA – Pan-genome Graph Algorithms and Data Integration
    Responsible: Prof. Dr. A. Schönhuth (coordinator), Prof. Dr. J. Stoye
    Funded by: European Commission (EU H2020, RISE)
  • RaPEQ3 - Rapssaat als einheimische Quelle von hochwertigen Protein für die menschliche Ernährung
    Funded by: Federal Ministry of Education and Research (BMBF)
    Resonsible: Prof. Dr. Bernd Weisshaar
  • Stabilität und Vererbbarkeit von DNA-Methylierungsmustern in Zuckerrübe: Einfluss auf phänotypische Plastizität, TE-Aktivitäten und Potential für die Züchtung
    Funded by: Federal Ministry of Education and Research (BMBF)
    Resonsible: Prof. Dr. Bernd Weisshaar
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